CAS 128446-35-5 HPBCD For Improving Drug Solubility Stability And Reduced Side Effects

Technical Parameter

Product Name: Hydroxypropyl Beta Cyclodextrin

Other Name: 2-Hydroxypropyl Beta Cyclodextrin,Hydroxypropyl Betadex,Hydroxypropyl Cyclodextrin

CAS NO.: 128446-35-5

Technical Standards

Product Introduction

Natural Cyclodextrin:

• Alpha Cyclodextrin CAS 10016-20-3
• Beta Cyclodextrin CAS 7585-39-9
• Gamma Cyclodextrin CAS 17465-86-0

Cyclodextrin Derivatives & Compounds:

• Hydroxypropyl Beta Cyclodextrin                      Hydroxypropyl Beta Cyclodextrin Solution
• Piroxicam Beta Cyclodextrin                             2,6-Dimethyl Beta Cyclodextrin
• Carboxymethyl Beta Cyclodextrin                     2-Hydroxypropyl Beta Cyclodextrin
• Methyl Beta Cyclodextrin                                  Glucosyl Beta Cyclodextrin
• Hydroxyethyl Beta Cyciodextrin                        

• Hydroxypropyl Alpha Cyclodextrin                   Hydroxypropyl Gamma Cyclodextrin      

Product Features

1. Enhance corneal permeability of drugs
Hydroxypropyl cyclodextrin can enhance the corneal permeability of drugs. For example, hydroxypropyl beta cyclodextrin can increase the corneal penetration rate of pilocarpine nitrate by nearly 4 times.
2. Adjust drug release speed
For drugs that are generally taken, the inclusion effect of hydroxypropyl betacyclodextrin on drugs can achieve four types of controlled release effects, namely immediate release, delayed release (time-controlled release), extended release and controlled release.
3. Increase drug solubility and improve bioavailability
‌Hydroxypropyl-beta-cyclodextrin (HPBCD)‌ exhibits high hydrophilicity, which facilitates rapid drug dissolution in the gastrointestinal tract. This property significantly enhances the drug’s aqueous solubility, thereby improving its bioavailability. As a result, the therapeutic efficacy of the drug is amplified, allowing for reduced dosage requirements while maintaining or even enhancing clinical effectiveness.

Product Description

Hydroxypropyl beta-cyclodextrin is a hydroxyalkylated derivative of beta-cyclodextrin. It has excellent water solubility (the solubility at room temperature is greater than 500mg/ml) and has a significant solubilizing effect on drugs that are poorly soluble in water. It has been used as a solubilizer for injections abroad. This excipient has been included in the supplement to the European Pharmacopoeia (4th edition). Since hydroxypropyl beta-cyclodextrin has good water solubility and a good solubilizing effect on poorly soluble drugs, many applicants have used this excipient to add drugs that are poorly soluble or slightly soluble in water to hydroxypropyl beta-cyclodextrin and apply for production according to registration category 5.

Product Pictures

Product Packaging

Company Profile

ZIBO WEYES NEW MATERIALS CO.,LTD is a series of high-tech enterprises integrating scientific research, production and sales, specializing in research and production of cyclodextrin and derivatives, food and cosmetic additives, nutritional supplements and other plant extracts.The company has built an auxiliary material production workshop in line with cGMP, equipped with advanced inspection and testing instruments and equipment, constantly studying the inclusion technology, and providing comprehensive cyclodextrin application technology solutions and OEM services.

Company Certificate

Logistics

By air, by express(DHL,FedEx,UPS.etc), by sea or other modes of transportation.

We will discuss and provide samples according to customer needs.

FAQ

Q1. Can I have a sample order for HYDROXYPROPYL-BETA-CYCLODEXTRIN?
A: Yes, we welcome sample order to test and check quality. Mixed samples are acceptable.

Q2. What about the lead time?
A: 3-5 days for Sample preparing ,8-10 working days for mass production.

Q3. Do you have any MOQ limit for Hydroxypropyl Beta Cyclodextrin order?
A: Low MOQ, 1kg for sample checking is available.

Q4. How do you ship the goods and how long does it take to arrive?
A: Ship by DHL, UPS, FedEx. It takes 3-5 days to arrive. Airline and sea shipping also optional.

Q5.What services do you have?
A:We provide excellent after-sales service; we offer productcustomization services.