Stable Inclusion Complexes with Gamma Cyclodextrin Pharma Grade for Reduced Volatility and Improved Bioavailability
The molecular shape of gamma cyclodextrin is a conical ring, with the special properties of hydrophobic inner cavity and hydrophilic outer cavity. It can encapsulate other molecules in its internal cavity to form a stable inclusion complex, reduce oxidation, passivate photosensitivity and heat sensitivity, reduce volatility, and can also mask odors, improve water solubility, and enhance bioavailability.
1.Technical Parameter
Name:gamma-cyclodextrin
Other name:γ-cyclodextrin,cyclomaltooctaose
Abbreviation:GCD
CAS:17465-86-0
Molecular formula:C48H80O40
Molecular weight:1297.12
Solubility(in 100cm3 solvent, at 25℃):water:>20 g Methanol:<1g DMSO: >20g
Quality:Pharma grade / food grade / industry grade
2.Standards(for food grade)
| Items |
Standard |
| Appearance |
white powder,insipid,innocent |
| Content(Among Total Sugar)% |
≥98% |
| Loss on Drying % |
≤11% |
| Residue on Ignition % |
≤0.1% |
| Heavy Metal(ppm) |
≤5ppm |
| Arsenic Salt(As)% |
≤0.0001% |
| Total Viable Bacteria Number |
＜1000 |
| Total Viable Count Fungi |
＜200 |
|
Salmonella
/E. Coli
|
Absent |
Storage: at room temperature, in tightly closed container.
3.gamma Cyclodextrin Derivatives
- Hydroxypropyl Gamma Cyclodextrin
- Sulfobutyl E ther Gamma Cyclodextrin Sodium
4.Application
1). In pharmaceutical field, Gamma Cyclodextrin pharmaceutical grade and medicine could produce inclusion compound,
which could:
- Make unstable medicine stable;
- Make deliquescing, sticky and liquid medicine more powder-like;
- Make insoluble or hard-soluble medicine soluble.
2). In pesticide field, Gamma Cyclodextrin pharmaceutical grade and medicine could produce inclusion compound
to make some pesticides store and increase insecticidal efficacy.
3). In food field,Gamma Cyclodextrin pharmaceutical grade could:
- Cover and remove peculiar smell;
- Improve and enhance food organization structure;
- Relieve and remove bitter and astringent;
- Anti-oxidation; E. keep and improve relish.
4). In daily chemical field, Gamma Cyclodextrin pharmaceutical grade could function as emulgator and quality improver in cosmetics production. It could also be applied in tooth paste and tooth powder as deodorant and preservative.
5). In environment-protection field, Gamma Cyclodextrin pharmaceutical grade could be applied as treatment of waste water with oil. Alpha Cyclodextrin water solution could be used to clean oil groove and recycle it to get fuel oil.
5.Packing&Shipping
By air, by express(DHL,FedEx,UPS.etc), by sea or other modes of transportation.
We will discuss and provide samples according to customer needs.
6.About us
ZIBO WEYES NEW MATERIALS CO.,LTD is a high-tech enterprises integrating scientific research, production and sales, specializing in the research and production of cyclodextrin and derivatives, food and cosmetic additives, nutritional supplements and other plant extracts.
Our company has built an auxiliary material production workshop in line with cGMP, equipped with advanced inspection and testing instruments and equipment, constantly studying the inclusion technology, and providing comprehensive cyclodextrin application technology solutions and OEM services.
7.Certificate
8.FAQ
Q: What's your MOQ ?
A: Our MOQ is 1kg.
Q:What is your delivery term and delivery period?
A:We accept FCA,FOB, DDP, etc. You can choose the one which is the most convenient or cost effective for you.
By Air about 10 days after the arrival of the payment, by sea according to the shipment date.
Q: Is there a discount ?
A: Yes, for larger quantity, we always support with better price.
Q:What's your main markets?
A:South&North America, Europe, Asia, Africa etc. Top customers among more than 80 countries, One-stop supplier.
Q: How to confirm the Product Quality before placing orders ?
A: You can get free samples for some proucts, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Q: What is the payment term?
A: T/T,L/C,Western Union
9.Contact
ZIBO WEYES NEW MATERIALS CO.,LTD
Email: cassie@zbweyes.com
Tel/WhatsApp/WeChat/Zalo: +86 19050316763
Contact: Cassie Ding
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