Alpha Cyclodextrin Can Improve The Solubility And Bioavailability Of Drugs
Technical Parameter
Product Name: Alpha Cyclodextrin
Other name : α-cyclodextrin ; cyclomaltohexaose
Abbreviation : ACD
CAS NO.: 10016-20-3
Appearance: White powder,sweet,insipid and innocuous
Molecular Formula:C36H60O30
Molecular Weight:972.84
Technical Standards
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Item
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Specification
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Appearance
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white powder, insipid, innocent
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Millipore Filter
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No background and spot color
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Specific rotation
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+147°~+152°
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pH
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5.0~8.0
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Chloride
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≤0.018%
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Content(Among Total Sugar) %
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≥98%
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Loss on Drying %
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≤11%
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Residue on Ignition %
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≤0.1%
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Heavy Metal(as Pd)%
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≤0.0005%
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Arsenic Salt(As)%
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≤0.0001%
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Total Viable Bacteria Number
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＜1000
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Total Viable Count Fungi
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＜200
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Storage: at room temperature, in tightly closed container.
Product Description
α-Cyclodextrin is an organic substance with the appearance of white crystals. It is also called: alpha cyclodextrin, cyclohexaose, cyclic maltohexaose. It is the general name for a series of cyclic oligosaccharides produced by amylose under the action of cyclodextrin glucosyltransferase produced by Bacillus.
Product Advantage
1. Improve Drug Solubility And Bioavailability
Alpha-cyclodextrin can form inclusion complexes with drug molecules, thereby improving the water solubility and stability of the drug. This inclusion complex not only increases the solubility of the drug, but also reduces the degradation of the drug during storage and use, thereby improving the bioavailability of the drug. This is especially important for drugs that are administered orally, as it can promote the absorption of the drug in the digestive tract and improve its bioavailability in the body.
2. Enhance The Stability Of Drugs
Alpha-cyclodextrin encloses drug molecules in its ring structure through inclusion complexation, reducing the contact between the drug and the external environment, thereby effectively protecting the drug ingredients and preventing them from degradation during storage and use.
This property is particularly important in the pharmaceutical industry, as it can extend the shelf life of the drug and ensure the safety and effectiveness of the drug when used.
3. Controlled Release
Alpha-cyclodextrin can be combined with other polymers to prepare drug carriers with controlled release properties. For example, supramolecular hydrogels formed by combining with heparin-modified polymers can achieve controlled release of drugs, thereby better controlling the release rate and time of drugs.
4. Targeted Drug Delivery
Alpha-cyclodextrin can bind to targeting molecules to enhance the targeting of drugs. This property enables drugs to reach the lesion site more accurately, improve the therapeutic effect, and reduce damage to normal tissues.
Product Pictures
Product Packaging
Company Profile
ZIBO WEYES NEW MATERIALS CO.,LTD is a series of high-tech enterprises integrating scientific research, production and sales, specializing in research and production of cyclodextrin and derivatives, food and cosmetic additives, nutritional supplements and other plant extracts.The company has built an auxiliary material production workshop in line with cGMP, equipped with advanced inspection and testing instruments and equipment, constantly studying the inclusion technology, and providing comprehensive cyclodextrin application technology solutions and OEM services.
Company Certificate
Logistics
By air, by express(DHL,FedEx,UPS.etc), by sea or other modes of transportation.
We will discuss and provide samples according to customer needs.
FAQ
Q1. Can I have a sample order for Alpha Cyclodextrin?
A: Yes, we welcome sample order to test and check quality. Mixed samples are acceptable.
Q2. What about the lead time?
A: 3-5 days for Sample preparing ,8-10 working days for mass production.
Q3. Do you have any MOQ limit for Alpha Cyclodextrin order?
A: Low MOQ, 1kg for sample checking is available.
Q4. How do you ship the goods and how long does it take to arrive?
A: Ship by DHL, UPS, FedEx. It takes 3-5 days to arrive. Airline and sea shipping also optional.
Q5: What product certificates can you provide?
A: ISO,CDE registration number,FDA,HALAL,KOSHER and GMP Standards.
Q6.What services do you have?
A:We provide excellent after-sales service; we offer productcustomization services.
Contact
ZIBO WEYES NEW MATERIALS CO.,LTD
Email: katrina@zbweyes.com
Tel/WhatsApp/Wechat:+86 19054767765
Contact: Katrina
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