White Gamma Cyclodextrin Masking The Unpleasant Or Bitter Taste Of Medicines
Product Introduction
γ-cyclodextrin has a larger cavity than b-cyclodextrin, so the cavity can contain a wider range of guest molecules; it has better water solubility. At room temperature 25°C, the solubility of γ-cyclodextrin is 25.6g/100ml, while the solubility of α-cyclodextrin is 12.7g/100ml water and the solubility of b-cyclodextrin is only 1.88g/100ml water. Its application prospects are broader than those of b-cyclodextrin, but currently due to its small production scale, its price is high, which limits the promotion of its application.
Technical Parameters
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Item
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Specification
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Appearance
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white powder, insipid, innocent
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Millipore Filter
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No background and spot color
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Loss on Drying %
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≤11%
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Arsenic Salt(As)%
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≤0.0001%
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Content(Among Total Sugar) %
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≥98%
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Total Viable Count Fungi
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＜200
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Residue on Ignition %
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≤0.1%
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Total Viable Bacteria Number
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＜1000
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Heavy Metal(ppm)
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≤5ppm
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Product Application
1. Improve Drug Solubility And Bioavailability
The hydrophobic cavity can enclose poorly soluble drug molecules to form a stable inclusion complex, promote the dispersion and dissolution of drugs in water, and significantly improve bioavailability.
2. Enhance Drug Stability
The inclusion structure can block external factors such as light, oxygen, and moisture, reduce drug hydrolysis, oxidation or isomerization, and extend the storage life of raw materials and preparations.
3. Targeted Delivery And Reduction Of Toxic And Side Effects
Through surface modification, specific binding to diseased tissues can be achieved to improve targeting; at the same time, direct contact between drugs and normal tissues can be reduced to reduce toxic and side effects.
4. Taste Masking And Dosage Form Improvement
Mask the peculiar smell or bitterness of the drug to improve oral compliance; liquid or viscous drugs can also be powdered to facilitate preparation processing.
Product Advantage
1. Structural Characteristics
It is composed of 8 glucose units, and the diameter of the hydrophobic cavity is larger than that of α and β types, which can accommodate drugs with larger molecular weight or complex compounds.
2. Excellent Water Solubility
The solubility is 25.6 g/100 mL at 25°C, which is significantly higher than β-cyclodextrin (1.88 g/100 mL), and is more suitable for the development of high-concentration preparations.
3. High Safety
After chemical modification (such as hydroxypropylation), the toxicity is lower, and some derivatives (such as HPβCD) have been approved by the FDA for high-end dosage forms such as injections.
4. Multifunctional Adaptability
It can combine polar and non-polar groups in drug molecules at the same time, and is suitable for the inclusion needs of various APIs such as antibiotics, anticancer drugs, and vitamins.
Product Packaging
Product Pictures
Company Profile
ZIBO WEYES NEW MATERIALS CO.,LTD is a series of high-tech enterprises integrating scientific research, production and sales, specializing in research and production of cyclodextrin and derivatives, food and cosmetic additives, nutritional supplements and other plant extracts.The company has built an auxiliary material production workshop in line with cGMP, equipped with advanced inspection and testing instruments and equipment, constantly studying the inclusion technology, and providing comprehensive cyclodextrin application technology solutions and OEM services.
Company Certificate
Logistics
By air, by express(DHL,FedEx,UPS.etc), by sea or other modes of transportation.
We will discuss and provide samples according to customer needs.
FAQ
Q1. Can I have a sample order for Gamma Cyclodextrin?
A: Yes, we welcome sample order to test and check quality. Mixed samples are acceptable.
Q2. What about the lead time?
A: 3-5 days for Sample preparing ,8-10 working days for mass production.
Q3. Do you have any MOQ limit for Gamma Cyclodextrin order?
A: Low MOQ, 1kg for sample checking is available.
Q4. How do you ship the goods and how long does it take to arrive?
A: Ship by DHL, UPS, FedEx. It takes 3-5 days to arrive. Airline and sea shipping also optional.
Q5.What services do you have?
A:We provide excellent after-sales service; we offer productcustomization services.
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